MARBLES is a groundbreaking €7.5 million project, spanning five years with support from the EU, set to make waves in the world of sustainable bioprospecting. By exploring the untapped wealth of marine microbes, MARBLES aims to discover new bioactive compounds and microbial consortia that could revolutionize aquaculture, farming, and healthcare. With cutting-edge genomics and novel bioactive-compounds elicitors, MARBLES promises not just to unveil new environmentally friendly solutions for disease control but also to align with key UN goals, marking a new chapter in our quest for sustainable industry solutions.
As a partner in MARBLES 3BIO is responsible for creating strategies that evaluate the project's environmental and societal effects, ensure it meets regulations, and assess product safety and market viability. 3BIO’s expertise is especially critical in navigating international regulations like the Nagoya Protocol and fostering dialogue with policy experts and stakeholders to align scientific advancements with global sustainability goals.
BlueRemediomics is an innovative European project uniting 25 partners from 13 countries delving into the ocean's untapped marine microbial communities to boost the European blue economy. The project will establish a bioinformatics platform and cutting-edge culturomics to discover and develop marine microbial products, focusing on sustainability and equitable resource access. Bridging discovery with application, BlueRemediomics is set to accelerate product development and set new standards in marine biodiscovery, balancing ecological stewardship with intellectual property rights.
As BlueRemediomics beneficiary, 3BIO is pivotal in ensuring the project's alignment with Access and Benefit Sharing (ABS) regulations and broader scientific compliance. 3BIO is involved in shaping new policies for ABS and intellectual property, fostering innovative governance for ocean genetic resources, and positioning BlueRemediomics at the forefront of responsible marine biodiscovery.
The Micro4Biogas project is dedicated to advancing the biogas sector in Europe by optimizing biogas production by combining selected natural and synthetic microbial strains and consortia. Recognizing the urgent need to shift from polluting fossil fuels to renewable energy sources, the project aims to significantly increase the yield, speed, quality, and reproducibility of biogas production. The project’s innovative approach seeks to establish biogas as a competitive, sustainable, and viable renewable energy option, playing a crucial role in Europe's transition towards cleaner energy solutions and addressing the global energy and climate crisis.
In the Micro4Biogas project, 3BIO leads critical business-oriented aspects. 3BIO’s responsibilities include conducting in-depth market research on the biogas sector, developing robust business models and strategies, and managing intellectual property issues. This role positions 3BIO as a driver in aligning the project's scientific advancements with market viability and strategic business planning.
The HOTBIO consortium will train a new generation of scientists in transforming marine microbial natural products from deep-sea discoveries to medical applications. Involving 13 PhD students hosted by 11 European beneficiaries, the program covers all stages of the drug development pipeline – from microbial isolation and compound purification to creating drug-like analogues. The training includes skills in access and benefit-sharing, intellectual property, and entrepreneurship, preparing graduates for the competitive labour market with multidisciplinary experience in academic and industrial settings, supported by mentorship from industry experts and MSCA ITN MarPipe alumnae.
Within the HOTBIO project, 3BIO bridges the gap between lab discoveries and societal applications and training of two Early-Stage Researchers, focusing on the practical aspects of marine natural products, including their landscaping and licensing. Additionally, 3BIO hosts ESR secondments, offering these researchers valuable experiences and insights into relevant legal frameworks such as biosafety, IPR and ABS and about entrepreneurship, business and negotiations, thereby enriching their professional development and the overall impact of the HOTBIO project.
EATFISH, supported by the EU's Marie Skłodowska–Curie program, is a pioneering project with the aim of transforming European aquaculture into a sustainable and profitable industry. As an interdisciplinary project, EATFISH will train a new generation of scientists in sustainable aquaculture, addressing both environmental and consumer needs. By blending biology, technology, socioeconomics, and governance, the project aims to optimize resource use, promote animal welfare, and develop innovative products while refining governance strategies.
3BIO has a multifaceted role within EATFISH focused on enhancing the valorisation potential of innovations, with a particular emphasis on value capture and fostering entrepreneurial skills among Early-Stage Researchers (ESRs). This exposure is crucial for equipping young scientists with practical experience and understanding of entrepreneurship, particularly in the context of the Norwegian salmon industry and the wider aquaculture sector.
The SEAWEEDforBangladesh project, backed by the Dutch Embassy in Dhaka and led by 3BIO, represents a significant step in harnessing the Bay of Bengal's rich seaweed diversity for Bangladesh's emerging blue biotechnology sector. With over 220 native seaweed species in Bangladesh, 3BIO's marine genetic resources scoping study has paved the way for sustainable seaweed cultivation, simultaneously boosting environmental health and bolstering coastal resilience. The project also explored seaweed's versatile applications across industries like animal feed, cosmetics, and bioremediation, propelling Bangladesh towards a sustainable blue economy and setting a precedent in marine genetic resource utilization.
In the second phase of the project, 3BIO will support local industry in farming red seaweed and in processing these red seaweeds into agar agar, an important food ingredient for the Muslim population of Bangladesh.
The NYMPHE project, funded by the European Union, represents a groundbreaking environmental restoration and sustainability effort. The core focus of the 17 partners is addressing the escalating issue of environmental contamination that impacts climate change, food security, and human well-being. NYMPHE aims to revitalize lands and waters severely affected by pollution by harnessing the power of innovative, nature-based bioremediation solutions. This initiative underscores the critical need to mitigate the adverse effects of human activity on the environment, striving for a healthier, more sustainable future. 3BIO experts play a crucial role in the project by providing insights into the regulatory requirements for executing R&D with microorganisms, genetically evolved organisms, and genetically modified organisms. A second task is to do a societal assessment of bioremediation strategies.
At the heart of NYMPHE's approach is the utilization of bioremediation, a biotechnological method that leverages the natural abilities of micro- and macroorganisms, plants, and enzymes. This method is uniquely designed to absorb, accumulate, and degrade pollutants and toxins from various environments, including soil, water, and beyond. NYMPHE's strategies are meticulously tailored to remove common pollutants like pharmaceuticals, microplastics, and heavy metals, employing a range of biologics such as enzymes, bacteria, fungi, and plants. The ambitious project aims to eliminate at least 90% of pollutants in tested sites across Europe, significantly enhancing biodiversity and achieving environmental quality standards close to those of Natura 2000.
An inventive effort that takes a big step toward diverse and sustainable EU in-land aquaculture is the INNOAQUA project. Its primary focus is integrating algae into sustainable aquaculture practices and developing high-value food applications. With 17 partners collaborating, INNOAQUA aims to demonstrate and mainstream innovative algae-based foods and solutions underpinned by ecology, circularity, and digitalization concepts. This project signifies a paradigm shift in sustainable aquaculture, targeting a more eco-friendly and efficient industry. 3BIO will perform a regulatory (safety/health/environmental) assessment to identify relevant legislation and potential regulatory hurdles for the technology and products developed by the other INNOAQUA Partners.
The innovative approach of INNOAQUA’s value chain faces several safety issues (e.g., related to the choice of organisms and production infrastructure) and regulatory requirements for the operation and marketability of the products. Regulatory requirements, especially for innovative cultivation techniques and novel food applications, may represent one of the most relevant hurdles impacting the viability of the solutions. Thus, addressing such aspects early will significantly enhance the chance for success while providing essential information for exploiting business cases.
INNOAQUA's objectives are multi-faceted and aimed at transforming the aquaculture industry. These include implementing an ecosystem approach for sustainable management of aquaculture production, demonstrating tools to reduce waste in cultivation and processing, and developing innovative algae-based seafood products. Additionally, the project focuses on enhancing societal acceptance and market penetration of these innovative products through novel social simulation approaches and maximizing the broader uptake of INNOAQUA’s results during and after the project’s execution. This holistic approach ensures environmental sustainability and aquaculture practices' economic viability and social acceptability.